A vectorised function to calculate SOFT Scores for predicting patient survival after liver transplantation The units for donor serum creatinine are in µmol/l and recipient serum albumin in g/l but they can be changed to mg/dl and g/dl respectively by setting the Units parameter to "US".

soft(Age, BMI, PrevTx, AbdoSurg, Albumin, Dx, ICU, Admitted, MELD,
  LifeSupport, Encephalopathy, PVThrombosis, Ascites, PortalBleed,
  DonorAge, DonorCVA, DonorSCr, National, CIT, Units = "SI")

Arguments

Age

numeric vector of patient ages in years

BMI

numeric vector of patient BMI in kg/m2

PrevTx

numeric vector of number of previous transplants

AbdoSurg

numeric vector of whether previous abdominal surgery (1 = "yes", 0 = "no")

Albumin

numeric vector of serum albumin in g/l

Dx

numeric vector of whether on dialysis before transplant (1 = "yes", 0 = "no")

ICU

numeric vector of whether patients in intensive care unit before transplant (1 = "yes", 0 = "no")

Admitted

numeric vector of whether admitted to hospital pre-transplant (1 = "yes", 0 = "no")

MELD

numeric vector of MELD scores

LifeSupport

numeric vector of whether on life support pre-transplant (1 = "yes", 0 = "no")

Encephalopathy

numeric vector of whether encephalopathy present (1 = "yes", 0 = "no")

PVThrombosis

numeric vector of whether portal vein thrombosis (1 = "yes", 0 = "no")

Ascites

numeric vector of whether ascites pre-transplant (1 = "yes", 0 = "no")

PortalBleed

numeric vector of whether portal bleeding in 48 hours pre-transplant (1 = "yes", 0 = "no")

DonorAge

numeric vector of donor ages in years

DonorCVA

numeric vector of whether donor cause of death is CVA/stroke (1 = "yes", 0 = "no")

DonorSCr

numeric vector of donor terminal serum creatinine

National

numeric vector of whether national allocation (1 = "yes", 0 = "no")

CIT

numeric vector of cold ischaemic time in hours

Units

units to use for creatinine and albumin, "SI" (default) for µmol/l and g/l, "US" for mg/dl and g/dl

Value

numeric vector of SOFT Scores

Details

Reference: Rana A, Hardy MA, Halazun KJ, et al. Survival Outcomes Following Liver Transplantation (SOFT) Score: A Novel Method to Predict Patient Survival Following Liver Transplantation. American Journal of Transplantation 2008; 8:2537-2546.

Examples

soft(Age = 35, BMI = 20, PrevTx = 0, AbdoSurg = 1, Albumin = 30, Dx = 0, ICU = 0, Admitted = 0, MELD = 29, LifeSupport = 0, Encephalopathy = 1, PVThrombosis = 0, Ascites = 1, PortalBleed = 0, DonorAge = 44, DonorCVA = 0, DonorSCr = 110, National = 0, CIT = 8) # 7
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